Ciclopirox Olamine 1% w/w Cream.
YESPIROX-1 Cream.
YESPIROX-1 is an anti-fungal cream with Ciclopirox Olamine 1% w/w, from Bioglint Derma Care. Ciclopirox belongs to a class of hydroxypyridone antifungals with a different mechanism of action than both azoles and allylamines, which makes it highly effective in treating fungi that are resistant or insufficiently treated with other types of antifungals. As opposed to both Ketoconazole and Terbinafine, Ciclopirox does not prevent ergosterol biosynthesis, but binds to polyvalent cations necessary for the functioning of multiple enzymatic systems and displays broad-spectrum activity against fungi and bacteria. Ciclopirox Olamine 1% w/w Cream is recommended by dermatologists for treatment of tinea infections, cutaneous candidiasis and pityriasis versicolor.
Ciclopirox Olamine 1% w/w Cream is one of the YESPIROX antifungal preparation line from Bioglint Derma Care available through the Derma PCD Franchise network in India.
Uses and Indications
Ciclopirox Olamine 1% w/w Cream is recommended by dermatologists and doctors to be used as a topical agent in the management of the following disorders:
- Tinea corporis (body ringworm) — a dermatophyte infection with characteristic ring-shaped lesions
- Tinea cruris (jock itch) — a groin infection caused by fungus
- Tinea pedis (athlete’s foot) — a dermatophyte infection involving the interdigital spaces, plantar surfaces, and lateral aspects of the feet
- Tinea versicolor (pityriasis versicolor) — a skin discolouration due to Malassezia infection
- Cutaneous candidiasis — Candida infections of intertriginous areas and skin folds
- Seborrhoeic dermatitis — a dermatitis of the scalp and face due to Malassezia proliferation
- Onychomycosis (fungal nail infection) — in combination with systemic therapy of choice
- Skin infection with a mixed population of bacteria and fungi — antibacterial property of Ciclopirox is useful in this scenario
How Ciclopirox Olamine 1% w/w Cream Works
The mechanism of action of Ciclopirox Olamine is highly unique because this drug acts by a multi-target mechanism, which distinguishes it from all other topical antifungal drugs available on the market. Instead of affecting one enzyme or metabolic pathway only, Ciclopirox chelates trivalent cations, such as iron (Fe³⁺) and aluminium (Al³⁺), which serve as cofactors of several enzyme systems required for proper functioning of the fungus, including peroxidases, catalases, and cytochrome enzymes associated with the electron transport chain. Ciclopirox, therefore, inhibits fungal respiration, mitochondrial functioning, DNA repair, and cell membrane stability through its multiple targets. It is practically impossible to develop resistance to Ciclopirox because no mutations can be induced that will make the fungus resistant to all these targets of Ciclopirox. Moreover, Ciclopirox possesses anti-bacterial activity against both gram-positive and gram-negative bacteria, which makes YESPIROX-1 effective in mixed fungal and bacterial infections.
Dosage and Administration
Ciclopirox Olamine 1% w/w Cream should be used topically only. Before using this drug, it is important to clean the affected area and completely dry it. Then apply a thin layer to the infected skin and skin within 1 cm around it, and massage it in, one or two times a day according to the dermatologist’s recommendation. The recommended course of treatment is 2 to 4 weeks for tinea, 4 weeks for cutaneous candidiasis, and longer for seborrhoeic dermatitis. Do not apply this medicine close to your eyes, mucous membranes or on open wounds, unless otherwise directed.
Side Effects
Ciclopirox Olamine 1% w/w Cream is generally very well tolerated. Localised skin reactions at the application site may rarely include:
- Mild burning, stinging, or itching sensation on application
- Erythema (redness) or skin irritation in sensitive individuals
- Contact dermatitis in rare cases of hypersensitivity to Ciclopirox
- Mild dryness or peeling at the application site
Discontinue use and consult a dermatologist if significant skin irritation or allergic reaction develops.
Precautions and Warnings
- For external use only. Do not come into contact with eyes and mucous membranes.
- Tell your dermatologist if you have known allergies to Ciclopirox or hydroxypyridone antifungals.
- Do not apply under occlusive dressing unless directed by your doctor.
- Avoid use on the face without the consent of the dermatologist.
- Patients who are pregnant and lactating must use the product only after proper consultation with a doctor.
- Wash your hands before and after use to prevent contamination.
- Do not use the same tube by sharing it with other people to avoid infection.
- Visit your dermatologist if there is no improvement even after 4 weeks of use.
- Keep away from children.
Storage Instructions
Store below 25°C in a cool and dry place, protected from direct sunlight and moisture. Keep the cap tightly closed after use. Store out of reach of children.
Derma PCD Franchise for Ciclopirox Olamine 1% w/w Cream – Bioglint Derma Care
Bioglint Derma Care invites pharma professionals, distributors, and derma franchise partners across India to partner for the Derma PCD Franchise of YESPIROX-1 Cream and the complete Bioglint YESPIROX antifungal range. Ciclopirox-based products are increasingly prescribed by dermatologists for their unique multi-target mechanism, broad-spectrum activity, and superior profile in mixed fungal-bacterial infections — making YESPIROX-1 a differentiated and clinically compelling addition to any derma franchise portfolio.
Why Choose Bioglint Derma Care for Derma PCD Franchise?
- Exclusive monopoly-based PCD Franchise for YESPIROX-1 and the entire Bioglint family for your district or state
- Full-fledged derma range including creams, ointments, gels, face wash, shampoo, soap, tablets, capsules, and dusting powder
- Highly efficient manufacturing with product effectiveness and safety
- Profitable margins and competitive pricing for all derma products
- No cost promotion material including visuals, MR bag, samples, reminder card, and literature
- Nationwide shipping with strong logistics and prompt order fulfilment
- Trained franchise support team for business support
Who Can Apply?
- Pharma professionals and distributors looking to expand their antifungal derma portfolio
- Medical representatives seeking monopoly-based Derma PCD franchise opportunities
- Existing franchise partners wanting differentiated antifungal products beyond standard Ketoconazole and Terbinafine
Disclaimer: YESPIROX-1 Cream is a dermatological product. Use under the supervision of a registered dermatologist or medical practitioner. This document is for informational and Derma PCD Franchise marketing purposes only and does not constitute medical advice.
